猪辅助性异位部分肝移植供肝的修整和断面处理

THE REDUCING SIZE METHOD AND MANGAGEMENT OF CUTTING SURFACE OF DONOR LIVER IN AUXILIARY HETEROTOPIC PARTIAL LIVER TRANSPLANTATION IN PIG

目的 探讨辅助性异位部分肝移植 (AHPL T)供肝的修整和断面处理方法。方法 按照猪肝脏的解剖结构 ,切除左半肝 ,将供肝右半肝植入受体右肝下 ,观察受体存活率、肝功能、供肝胆汁分泌情况及病理改变 ;分组按不同方法处理供肝断面 ,A组单纯缝扎 ,B超用大网膜衬垫后缝扎加医用胶涂布 ,观察断面的处理效果 ;分析总结。结果 1.用供肝右半肝植入的方法 ,行 AHPL T的肝衰受体存活率和肝功能显著优于肝衰模型组 ,植入肝脏胆汁分泌和肝细胞存活良好。 2 .B组供肝断面的撕裂机率和出血率、腹腔出血率、出血所致的病死率均显著低于 A组。结论 AL PL T时 ,用供肝右半肝植入是合适的 ;供肝断面应在衬垫下缝扎 。

Objective To investigate the reducing size method and management of cutting surface of donor liver in au xiliary heterotopic partial liver transplantation in pig.Methods According to the property of pig's liver construction,the left half liver is removed,the right half liver is transplanted under the host's right liver ,host's surviving rate,liver function,bile secretion and pathology of donor liver are investigated.Two kinds of management of cutting surface of donor liver are used,Group A:the surface is sewed and ligated simply;Group B:the surface is sewed and ligated with caul underlay,and gelatinized with medical gum;effect is investigated.Results 1,When the right half liver is transplanted in AHPLT,host's surviving rate and liver function is superior to contral group,the bile secretion and hepatocyte surviving of donor liver liver are good.2,Bleeding and rapture rates of cutting surface of donor liver is lower in Group B than that in Group B.Conclusions 1,The right hailf liver transplanted is proper in AHPLT.2,the cutting surface of donor liver should be sewed and ligated with caul underlay,and gelatinized with medial gum.