脑梗死和TIA患者血液流变学变化的对比研究

Comparative study of hemorheological alterations in cerebral infarction and tia

目的 :研究脑梗死和短暂性脑缺血发作 (TIA)患者的血液流变学改变及其临床意义。方法 :将91例脑梗死患者和 4 0例TIA患者的血液流变学指标与正常对照组进行比较分析。结果 :脑梗死组的各项血液流变学指标明显高于对照组 (P <0 .0 5 ,P <0 .0 1) ;TIA组的全血粘度和血浆粘度升高 ,与对照组相比有统计学意义 (P <0 .0 5 )。结论 :红细胞压积和纤维蛋白原含量的升高是造成血液粘度增高的重要因素。

Objective: To study the hemorheological alterations and their clinical significance of cerebral infarction and transient ischemic attack(TIA). Methods: The hemorheological indexs were measured in 91 cases with cerebral infarction and 40 TIA cases and were compared with those of the normal controls. Results:The hemorheological indexs of cerebral infarction group were significantly higher than those of the normal controls(P<0.05,P<0.01);the whole blood viscosity and plasma viscosity of TIA group increased markedly (P<0.05). Conclusion:Elevated hematocrit and fibrinogen levels were the main factors causing an increase in blood viscosity.