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孕妇外周血中胎儿红细胞分离方法研究进展

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摘要 孕妇外周血中分离胎儿细胞进行基因分析是目前创伤性最小的方法 ,随着物理学、遗传学、免疫学和分子生物学理论技术的发展及应用 ,对胎儿红细胞标志物的认识能力显著提高 ,分离胎儿细胞的方法明显改善 ,可望将少量的胎儿细胞从大量的孕妇外周血细胞中高纯度地分离出 ,用于非创伤性的产前基因诊断。
出处 《国外医学(临床生物化学与检验学分册)》 2002年第3期153-154,共2页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
基金 甘肃省自然科学基金资助课题 (编号 :ZR 96 0 93)
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参考文献15

  • 1Lamvu G, Kullre JA. Prenatnl diagnosis useing fetal cell from maternal circulation[J]. Obster Gynecol Suyv, 1997,52(7) :433-437.
  • 2Sargent IL, Johansen M, Chau S, et al. Clinical experience:Isolating trophoblasts from maternal blood[J]. Ann NY Acad Sci, 1994,731:154-161.
  • 3Goldberg JD, Wohlferd MM. Incidence and outcome of chromosomal mosaicism found at time of chorionic villius sampling[J]. Am J Obster Gynecol, 1997,176:1349-1353.
  • 4Bianchi DW, Zickwolf GK, Weil GJ, et al. Male fetal progenitor cells persist in maternal blood for as long as 27years postpartum[J]. Proc Natl Acad Sci USA, 1996,93:705-708.
  • 5Holzgreve W, Troeger C, Schatt S, et al. Prenatal diagnosis with fetal cells in maternal blood: report of experiences in Basal[J]. Schweiz Med Wochenschr, 1998, 128 (43):1641-1645.
  • 6Bianchi DW. Prenatal diagnosis by analysis of fetal cells in maternal blood[J]. J Pediatric, 1995,127: 847-856.
  • 7Hengstschlager M,Bernaschek G. Fetal cells in the peripheral blood of pregnant women express thymidine kinase: a new marker for detection[J]. FEBS Letter, 1997,404: 299-302.
  • 8Bohomer RM, Zhem D, Bianci DW. Identification of fetal nucleated red blood cells in cocultures from fetal and adult peripheral blood:differential effects of serum on fetal and adult erythropoiesis[J]. Prenal Diagn, 1999,19(7): 628-636.
  • 9Troeger C, Holzgreve W, Hahn S. A comparison of different density grandients and antibodies for enrichment of fetal erythroblasts by MACS[J]. Pretal Diagn,1999,19(6):521-526.
  • 10Sekizawa A, Farina A, Zhen DK, et al. Improvement of fetal cell recovery from maternal blood: suitable density gradient for FACS separation[J]. Fetal Diagn her, 1999,14(4) :229-233.

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