老年原发性高血压并靶器官损害的临床研究

The clinical study in elderly hypertension with target organ damages

目的 :研究老年原发性高血压 (EH)并靶器官损害的临床特点。方法 :观察了 2 6 1例老年EH与 2 0 8例非老年EH患者的 2 4h动态血压、2 4h动态心电图、心脏B超、头颅CT或MRI及血液生化检查。结果 :单纯收缩期高血压及血压昼夜节律消失在老年EH组多见 ,并且老年EH尤其是血压昼夜节律消失者较非老年EH并发靶器官损害多见。结论 :老年EH具有单纯收缩期高血压多见的临床特点 ,其临床特点与并发靶器官损害相关。因此 ,临床应重视单纯收缩期高血压的治疗 ,并且在降压治疗过程中注意血压节律的调整。

Objective:To investigate the clinical characteristic in elderly hypertension with target organs damages. Method:ABPM, HOLTER, CT or MRI and blood biochemical measures were carried out in 261 elderly hypertension patients and 208 Controls. Result:Isolated hypertension and disappeared of blood pressure rhythms were common in elderly hypertension, moreover, target organ damages are more often in elderly hypertension than in controls, especially in elderly hypertension with disappeared of blood pressure rhythms.Conclusion:Isolated systolic hypertension and disappeared of blood pressure rhythms are clinical characteristics of elderly hypertension, which are related to target organs damages. Therefore, it is important to treat isolated hypertension and regulate blood pressure rhythms in clinical.