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食欲抑制型减肥药西布曲明 被引量：6

Sibutramine——a new anorectic
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摘要 西布曲明是一种新型食欲抑制型体重控制剂 ,它没有类似于安非他明的潜在成瘾性。在体内其活性代谢物二级胺M1及一级胺M2 可抑制 5 羟色胺及去甲肾上腺素的再摄取 ,通过增加饱胀感而抑制食欲 ,并诱导产热 ,增加能量消耗。临床研究显示其为有效安全的减肥药物。 Sibutramine is a new anorectic for weight control without amfetamine like abuse potential.Its active metabolite M 1 and M 2,inhibit the reuptake of 5 HT and noradrenaline and induce the anorectic effects.Clinical results showed that it could be an adjuvant for management of obesity.
作者 邹大进 王卓
机构地区 第二军医大学附属长海医院
出处 《中国新药杂志》 CAS CSCD 北大核心 2002年第3期200-203,共4页 Chinese Journal of New Drugs
关键词 西布曲明 食欲抑制剂 临床疗效 sibutramine anorectic clinical efficacy
分类号 R977 [医药卫生—药品]
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参考文献17

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同被引文献47

引证文献6

二级引证文献19

中国新药杂志
2002年 第3期

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