杏丁注射液治疗急性脑梗死92例临床疗效分析

Efficacy of Xingding injection in treatment of 92 patients with acute cerebral infarction

目的 :观察杏丁注射液治疗急性脑梗死的疗效。方法 :将入选患者按入院顺序随机分为杏丁注射液治疗组和复方丹参对照组 ,于d1,3,7,15分别进行神经功能缺损、临床疗效全面观察及治疗前后血液流变学相关指标、脑电功率谱、脑血流检测。结果 :治疗组全血粘度、血浆粘度、血小板聚集率、红细胞压积、红细胞电泳时间及脑电功率谱和脑血流均明显改善 ,与对照组相比有显著差异 ;治疗组有效率和总进步率都显著高于对照组 ;2组均无明显不良反应。结论 :杏丁注射液可作为急性脑梗死早期的治疗药物。

Objective:To investigate the efficacy of Xingding injection in treatment of acute cerebral infarction(ACI).Methods:The patients with ACI were radomly divided into Xingding injection(the therapy) group and Fufang danshen injection (the control) group according to hospitalized order.Nerve function deficit score,general investigation of clinically curative effect,blood rheology,electroencepha power gram,cerebral blood stream were respectively observed at d1,d3,d7,d15.Results:Total blood viscosity,blood plasma viscosity,blood platelet accumulated rate,hematocrit,red blood corpuscle electrophoresis time,electroencepha power gram and cerebral blood rheology in the therapy group were obviously improved after treatment.The changes in the therapy group were significantly superior to those in the control group.The effectiveness and total progress rate in the therapy group were better than that in the control group and no adverse reactions were observed in both groups.Conclusion:Xingding injection can be used in treatment of ACI in early stage.