利水逐瘀法治疗高血压性脑出血颅内压增高临床研究

Clinical study of the therapeutics of inducing diuresis and removing stasis in treating intracranial hypertension caused by hypertensive cerebral hemorrhage

目的 观察利水逐瘀法治疗高血压性脑出血颅内压增高的临床疗效。方法 1 0 0例高血压性脑出血颅内压增高患者随机分为治疗组和对照组 ,各 5 0例。对照组单纯西医常规治疗 ,治疗组在对照组西医常规治疗基础上配合利水逐瘀法。 2组均通过腰穿测定颅内压 ,头颅CT观察脑水肿 ,同时进行临床神经功能缺损程度评分 ,比较 2组疗效。结果 治疗组与对照组比较 ,脑水肿减轻 ,颅内压降低更明显 (P <0 .0 1 ) ,甘露醇用量明显减少(P <0 .0 1 ) ,降低了大剂量甘露醇对肾脏的毒副作用 ,促进了神经功能的及早恢复 ,降低死亡率、致残率。结论 在常规西医治疗的基础上配合利水逐瘀方法治疗高血压性脑出血颅内压增高 。

Objective To observe the therapeutic effect of the inducing diuresis and removing stasis in treating intracranial hypertensioncaused by hypertensive cerebral hemorrhage. Methods 50 patients in control group were treated with routine treatment of western medicine; 50 patients in treatment group,based on the treatment of routine western medicine, were treated with the therapeutics of indusing diuresis and removing stasis.The intracranial pressure in both groups were measured by lumbar puncture,and the CT of brain was conducted to observe the encephaledema,and the defective degree of nervous function was scored.Results The encephaledema of patients in treatment group was relieved,compared with that in control group, and intrac ranial pressure was reduced significantly(P<0.01).The dosage of diosmol was decreased significantly (P<0.01),as a results,whose side effects of diosmol on kidney was reduced,which promoted the recovery of nervous function, and decreased the mortality and deformity rate.Conclusion The therapeutics of inducing diuresis and removing stasis combined with routine western medicine in treating intracranial hypertension caused byhypertensive cerebral hemorrhage is more effectual than the treatment of independent routine western medicine.