合肥地区胆囊疾病的流行病学调查

An epidemic survey of gallbladder disease in Hefei district

目的通过合肥地区 6 94 6位健康人群的体检探讨各种良性胆囊疾病的发生情况 (包括已行胆道手术者 )以及高脂血症与胆囊结石的关系。方法采用腹部彩色多普勒B超检查发现胆囊疾病。以血液生化检测对比胆囊结石组 (10 5 1例 )与无胆囊结石的 (5 133例 )对照组高血脂的发生率。结果 6 94 6例被检人群中良性胆囊疾病发生率 2 1 5 5 % ;胆囊结石、胆囊息肉样病变、胆囊胆固醇沉着症、慢性胆囊炎、肝内胆管及总胆管结石发生率分别为 15 13%、3 39%、1 35 %、0 96 %、0 70 % ;胆囊结石占良性胆囊疾病的 70 2 % ;胆囊结石组与对照组的高血脂发生率分别为 5 6 9%、32 3% ,P <0 0 0 1差异有显著意义。结论本组工作提示 ,合肥地区工薪群体良性胆囊疾病特别是胆囊结石的发病率较高且与高血脂关系密切 。

Objective To evaluate the incidence of benign gallbladder disease and the relationship between the hyperlipidemia and gallbladder stone in Hefei district by a survey in 6?946 persons. Methods All benign gallbladder diseases were discovered by Colour Dopple ulterasound. The data of lipidemia were analyzed and a comparative study of 1?051 cases suffering from gallbladder stone with the control group was done. Results The morbidity of benign gallbladder diseases was 21 55%. The prevalence of gallbladder stone, gallbladder polypoid lesion, cholecystitis, intrahepatic cholelithiasis or choledocholithiasis were 15 13%, 3 39%, 1 35%, 0 96%, 0 70% respectively in all examined. The morbidity of gallbladder stone was 70 2% in the benign gallbladder diseases. The incidence of hyperlipidemia both in gallbladder stone group and control group were 56 9% and 32 3% ( P <0 001). Conclusion This study shows that the incidence of benign gallbladder disease with gallbladder stone in the citizen group of Hefei district was significantly higher than that of other district in China and the hyperlipidemia may be another risk factor of gallstone formation.