1070株葡萄球菌的分离鉴定和药敏性分析

Separation Identification and Analysis of Druggery Sensitivity of the 1 070 Staphylococci Strains

目的 了解和调查临床分离出的葡萄球菌的致病性及药敏情况 ,为有效控制致病性葡萄球菌提供参考方法 ,指导临床用药。方法 从医院住院病人的标本中分离出来 1 0 70株葡萄球菌进行详细检测 ,并进行 MRS检测、β-内酰胺酶试验、药敏试验 MIC测定。结果 在 1 0 70株葡萄球菌中 ,共分离出 1 3种细菌 ,其中凝固酶阳性者占 35 .2 % ,凝固酶阴性者占 64.8%。β-内酰胺酶试验阳性者占 72 .5 % ,β-内酰胺酶试验阴性者占 2 7.5 %。综合而看 ,葡萄球菌的耐药性均比较强 ,特别是 MRSA和 MRCNS。但所有葡萄球菌皆对万古霉素敏感。结论 葡萄球菌是造成医院感染的主要病原菌之一 ,合理使用抗生素对于有效治疗疾病和控制医院感染的发生至关重要 。

Objective To investigate and analyze morbidity and druggery sensitivity of the staphylococci strains separated from clinical specimens,to provide reference method for effective control morbidity of staphylococcus,and instruct physician to reasonable administer drugs.Methods 1 070 staphylococci strains separated from inpatient specimens were inspected and those MRS,β lactamase,druggery sensitivty MIC were tested.Results 13 kinds of germ were separated from 1 070 staphylococci strains.Among those test,positive thrombin was 35.2 percent,negative was 64.8 percent,positive β lactamase was 72.5 percent and negative was 27.5 percent.The drug resistance of these staphylococcus was to a large degree,especially better of the MRSA and MRCNS.But all these staphylococcus was sensitive to vancomycin.Conclusion Staphylococcus is one of the mostly germ bring on honspital infection.It is highly important to effectively treat disease and control hospital infection that physicians reasonable administer antibiotics.It should be emphasized the need for monitoring drug resistance of staphylococcus and instructing physician to reasonable administer drugs.