λ噬菌体阻遏蛋白与操纵基因相互作用的动力学研究

The Kinetic Study on the Interactions of λ cI Repressor Protein with Operator

根据 λ噬菌体阻遏蛋白与操纵基因的相互作用特点 ,提出了他们相互作用的化学动力学模型 .用此模型计算各结合位点饱和分数与阻遏蛋白浓度的关系函数 ,并对λ噬菌体阻遏蛋白与操纵基因相互作用的本征自由能及各位点间的偶联自由能进行了估算 。

According to the characteristics of the interactions of λ cI repressor proteins with operators,the chemical kinetic model of their interactions is proposed.The relations between the fractional saturation of every binding site and the concentrations of repressor proteins are given by using the model.And the intrinsic standard free energies of the interactions of λ cI repressor proteins with operators and the interaction energies of binding sites are calculated.These theoretical results are consistent with the experimental data.