高锰酸钾-硫代硫酸钠-延胡索乙素化学发光体系的研究

STUDY ON CHEMILUMINESCENCE KYSTEM OF POTASSIUM PERMANGANAATE-SODIUM THIOSULFATE-TETRAHYDROPALMATINE

采用流动注射技术研究了酸性条件下 ,延胡索乙素与高锰酸钾和硫代硫酸钠的化学发光行为 ,对影响化学发光强度的诸因素进行了实验和探讨 ,建立了流动注射化学发光法测定延胡索乙素的新方法 .方法的检出限为 3× 10 - 8g/mL ,线性范围为 1.0× 10 - 7～ 8.0× 10 - 5g/mL ,对 4 .0×10 - 6g/mL延胡索乙素进行 11次平行测定 ,相对标准偏差为 1.6 % .方法用于药剂中延胡索乙素的测定 。

An analytical method consisting of flow-injection samping and chemiluminescence detection for determination of tetrahhydropalmatine is described.It is based on the chemiluminescence reaction of KMnO 4-Na 2S 2O 3-tetrahydropalmatine system.The chemiluminescence intensity was correlated linearly with concentration of tetrahydropalmatine in the range of 0.1～80.0mg/L.The determination limit is 0.03mg/L.The relative standard deviation is 1.6% for 11 measurements of 4.0 mg/L tetrahydropalmatine standard solution.The method has been applied to the determination of tetrahydropalmatine in pharmaceutical preparations and the results are in good agreement with those by standard method.