Levovist声学造影在肾移植急性排斥诊断中的应用

Application of levovist echoangiography in diagnosis of acute rejection in transplanted kidneys

目的 评价levovist声学造影在移植肾急性排斥诊断中的作用。方法 对肾移植术后23例急性排斥和23例正常经过的病例定量静脉注射levovist声学造影,比较正常组与排斥组造影前后肾内血液面积比(BFAR)的变化和造影过程中血流信号增强的历时变化。结果 levovist声学造影可增强正常组和急性排斥组移植肾血流的检出率,两组的BFAR值均升高,但正常组造影前后BFAR的变化比急性排斥组更大。虽然两组的增强开始时间和增强峰值时间无统计学差异,但排斥组的增强持续时间比正常组明显延长。结论 levovist声学造影有助于肾移植术后急性排斥的诊断。

To investigate the value of levovist echoangiography in diagnosis of acute rejection in transplanted kidneys. Methods Echoangiography by intravenons injection of levovist was performed in 46 transplanted kidneys, 23 with acule rejection (rejection group) and the remaining 23 with non - rejection (normal group) . The changes in blood How area ratio(BFAR) following echoangiography and the dynamic changes in the enhancement of blood flow signals during echoangiography were evaluated. Results Levovist echoangiography increased the detection rate of blood flow signals in both rejection and normal groups. BFAR became elevated following echoangiography in two groups, and more remarkable in normal group. There was no significant difference between the starting time and peak time of enhancement in two groups, but the duration time was markedly prolonged in the rejection group. Conclusion Levovist echoangiography was helpful in the diagnosis of acute rejection in transplanted kidneys.