光学相干生物测量仪测量人工晶体度数的初步研究

Preliminary study of optical coherence interferometry for intraocular lens calculation

目的:通过比较光学相干生物测量仪（IOL Master）与传统人工晶体测量法对人工晶体度数测量的特点及准确性,评价新型光学相干生物测量仪的临床应用价值。方法:50例50只眼老年性白内障患者,术前分别应用IOL Master、超声波生物测量仪及角膜曲率计测量眼轴长度和角膜曲率。使用SRK-Ⅱ公式计算人工晶体度数。对患者施行超声乳化白内障摘除术后,按照超声波检查法得出的人工晶度数植入可折叠人工晶体。术后三个月随诊检查视力及眼屈光度。结果:超声波检查法和IOL Master检查得出的眼轴分别为23.59±0.89和23.64±0.80,两者对比差异无显著性（P=0.13）;角膜曲率计和IOL Master测量角膜曲率分别为44.05±2.05和43.99±2.16,两者对比差异无显著性（P=0.30）。术后3个月病人平均绝对屈光误差≤±0.5D和≤±1D各占94％和100％。结论:应用新型光学相干生物测量仪进行人工晶体度数测量,具有非接触性、高准确性、安全而病人易于接受的特点。

Objective: To evaluate the clinical feasibility of using a new optical coherence interferometry (IOL Master) comparing with traditional biometry in the accuracy and characteristics for intraocular lens (lOLs) calculation.Methods: The measurement of axial length was performed in 50 patients (50 eyes) with senile cataract using IOL Master and ultrasonic biometry, and the measurement of corneal power was also performed in the patient using IOL Master and manual keratometry preoperativ-ely. Phacoemulsification and foldable lens implantation were done on the patients. IOL power calculation was carried out according to the SRK-II formula on the basis of ultrasound data. The visual acuity and refractive outcome were follow-up after 3 months postoperation.Results: No significant difference between the two methods in axial length measurement which was 23.59 0.89mm by ultrasound and 23.64 0.80mm by IOL Master (P = 0.13), and in corneal power measurement which was 44.05 2.05 by keratometry and 43.99 2.16 by IOL master (P = 0.30). The mean absolute refractive error were within 0.5 diopter in 94 % and 1.0 diopter in 100 % . Conclusions: The new optical coherence interferometry is a noncontact, safe and patient-friendly method for IOL power calculation with high accuracy.