摘要
本文报导605例各期血吸虫病患者及227例疫区非血吸虫病居民血清HBV 标志物检查结果。急性及慢性早期血吸虫病患者各项 HBV 标志物与非血吸虫病人群比较无显著差异。晚期血吸虫病患者 HBsAg、抗-HBc 检出率显著高于其它三组人群。晚期血吸虫病患者伴血清 HBsAg 阳性者的肝功能损害较 HBsAg 阴性者严重。免疫组织化学研究证明晚期血吸虫病患者肝细胞内 HBsAg 检出率达63.3%。行脾切除术者与非手术者 HBV 标志物检出率之间无显著差异。作者认为,在各期血吸虫患者中,晚血合并 HBV 感染最严重,其原因尚待深入研究。
The serum HBV markers among 605 patients in different stages of schistosomiasis were investigated using a method of ELLSA.The presence of HBV markers among patients with acute and chronic schistomiasis was not significantly different from that of a control group,but the prevalence of HBV markers among patients with hepatosplenic schistomiasis was significantly higher than that of the other grottpS.A similar prevalence of HBsAg and HBcAb was found in patients with hepatosplenic schistomiasis and in patients alter splenectomy,the live function of patients with hepatosplemic schisto- somiasis who had positive HBsAg in serum was worse than that of patients without HBsAg.18.4% of misdiagnosis was found in 136 cases with hepatos- plenic schistosomiasis as proved by biopsy.An immunohistoehemical study showed 63.3% of the cases were positive for HBsAg in the liver ceils.
关键词
血吸虫病
HBV
肝炎
schistosomiasis/PA
hepatitis B virus/PY
hepatitis,viral,human/CO
