孕早期高危因素与不良妊娠结局关系的追踪研究

The longitudinal study of high-risk factors in the first trimester of pregnancy and pregnant abnormalities

目的 研究孕早期高危因素与不良妊娠结局之间的关系 ,为加强孕期保健提供依据。方法 以 2 0 0 0年 1月～ 2 0 0 0年 6月在铜陵市 30个妇幼保健网点进行孕期保健体检的孕早期妇女为研究对象 ,追踪观察至分娩 ,获得有效调查表 12 5 7份。结果 孕妇年龄 30岁以上、孕早期发热 38.5 0以上、孕早期阴道出血、HBe Ag阳性、既往异常妊娠史且生育间隔 2年以内、既往异常妊娠史且孕早期阴道出血等与不良结局的发生有密切统计学关联。结论 孕早期多种高危因素可增加不良妊娠结局的风险 。

Objective To study the relationships between the high risk factors in the first trimester of pregnancy and pregnant abnormalities, provide the evidence to strengthen the health care of pregnant women. Methods The cohort consisted of 1257 pregnant women who received pregnancy healthcare services in the 30 units of maternal and child health care of Tongling during Jan. to Jun. 2000, and observed the pregnant abnormalities caused by high risk factors in the first trimester pregnancy. Results It showed that high risk factors ,i.e.pregnant women over 30 years old,fever over 38.5℃,bleeding caused by threatened abortion,HbeAg positive and intervals of pregnancy less than 2 years combined with the history of pregnant abnormalities,bleeding caused by threatened abortion combined with the history of pregnant abnormalities et al. were related highly with the abnormal pregnancy outcomes. Conclusion:Various high risk factors in the first trimester of pregnancy may increase the risk of pregnant abnormalities and maternal health care should start from the first trimester of pregnancy.