长期口服避孕药妇女血压变化及其影响因素的分析

Effects of Long-term Oral Contraceptives on Women's Blood Pressdre

目的 研究长期服用避孕药对血压的影响。方法 对 340 0例使用国产避孕药 3～ 2 5年的健康育龄妇女及10 6 84例同期应用宫内节育器的血压变化和影响因素进行了分析。结果 长期服用避孕药妇女的血压值为SBP/DBP 12 7.0 / 83.5mmHg ,高于应用宫内节育器组的 12 0 / 79.5mmHg(P <0 0 1)。长期服药期间有 4 .2 %的妇女患高血压。是使用宫内节育器妇女的 4 .88倍 (0 .0 2 5 >P >0 0 1)。多元回归分析显示 :妇女年龄对血压的高低有较大影响 ,长期服用避孕药 15年以上者对血压的升高危险性更为明显。结论 长期服用避孕药物可能导致血压轻度升高。

Objective To study the effects of long term oral contraceptives on women's blood pressure. Methods Blood pressure changes in 3400 healthy women of childbearing age who have taken oral contraceptives for 3～25 years and another 10684 who have undergone insertions of intrauterine device (IUD) for 3～25 years were investigated. Results Average blood pressure of long term contraceptive taking women was 127/83.5 mmHg, higher than that of IUD using women, 120/79.5 mmHg( P <0 01).\ 4.26 per cent of long term contraceptive taking women developed hypertension,which was 4.88 times that of IUD\|using women(0 025> P >0 01). Multiple regression analysis revealed that age was an important factor influencing women's blood pressure and that women who have taken contraceptives over 15 years had a higher ridk for hypertension. Conclusion Long term oral contraceptives may result in slight elevation of blood pressure.