摘要
目的 :探讨利多卡因与度冷丁混合施行硬膜外麻醉术后镇痛的临床效果。方法 :选择ASAⅠ～Ⅱ级不同手术病人 5 0例 ,行硬膜外利多卡因麻醉 ,术后保留硬膜外导管行PCEA ,设定单次药量 5ml/次 ,锁定时间 6 0min ,镇痛液为 0 .5 %利多卡因 10 0ml+度冷丁 10 0mg +麻黄素 5 0mg。观察术后镇痛效果 (VAS法 )及恶心、呕吐、呼吸抑制、皮肤瘙痒等并发症情况。 结果 :全组病人均达到良好手术后镇痛效果 ,VAS评分 0～ 1分占 96 % ,2～ 3分占 4 % ,恶心、呕吐发生率均为 2 % ,无呼吸抑制和皮肤瘙痒。结论 :0 .5 %利多卡因和度冷丁混合应用于PCEA ,可取得良好临床镇痛效果 ,用药量小 。
Objective: To study the clinincal effect of ( PCEA) patient controlled epidural analgesia with lidocaine and meperidine. Methods:Fifty patients ASAⅠ～Ⅱgrade,had different operation under epiduralanesthesia with lidocaine.After operation, reserved epidural tube foradministering PCA,selected bolus dose 5ml,safe time 60min. Analgesic is 0.5% lidocaine 100ml+meperdine 100mg+ophedrinum 50mg.Recorded effect oranalgesia(VAS method)and side effect of nausea. Vomiting, respiratory despress and skin- titillated. Results: All patients had achieved satisfactory pain-controlled after operation.VAS grade in 0 ～1 code was 96%,2～3 code was 4%.None had respitory despress and skin- titillated.Conclusion:The mixture of 0.5% lidocaine and meperidine can achievecompletely pain-controlled through PCEA in clinic,less druge dose andless side effect. [
