摘要
苯乙酮与对甲氧基苯甲醛和芳香胺在少量浓盐酸或HCl-EtOH溶液催化下直接进行Mannich反应,用一步法合成了6个相应的Mannich碱,其中有3个是新的有机化合物,产率高达60%～73%.本文还对Mannich碱生成的条件进行了讨论.
In the presence of catalytic amount of concentrated hydrochloric acid or ethanolic-HCl solution. the Mannich reaction among acetophenone. methoxybenzaldehyde and arylamines was carried out directly to form six corresponding Mannich bases, in which there were three new compounds. The yields were 60%-73 %. The reaction conditions were discussed.
出处
《西南师范大学学报（自然科学版）》
CAS
CSCD
1991年第1期66-70,共5页
Journal of Southwest China Normal University(Natural Science Edition)
关键词
芳香胺
苯乙酮
MANNICH反应
Mannich reaction
Mannich bases
p-methoxybenzldehyde
arylamines
acetophenone
