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血液透析对终末期肾功能衰竭病人血清瘦素水平的影响

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摘要 目的:观察血液透析(HD)对终末期肾功能衰竭(ESRD)病人血清瘦素(Leptin)水平的影响,探讨其临床意义。方法:27例维持性HD患者按性别分两组,用ELISA方法分别测定其HD前血清Leptin浓度,将不同血流量和使用不同透析器情况下的Leptin浓度变化进行比较,分析HD前血清Leptin浓度与体重指数(BMI)、尿素清除指数(Kt/V)、年龄等的相关性。结果:HD不能有效降低血清瘦素水平;使用不同的透析器及增加透析时的血流量对血清瘦素水平无明显影响;血清瘦素水平与BMI有一定的相关性。结论:血清瘦素水平一定程度上反映病人的营养状况,HD不能有效降低血清瘦素水平。
出处 《实用医学杂志》 CAS 2002年第5期470-471,共2页 The Journal of Practical Medicine
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