摘要
光谱分析表明冰川棘豆生物碱结晶Ⅰ为含有1分子结晶水的2,2,6,6-四甲基-4哌啶酮（2,2,6,6-tetramethyl-4-piperidone,TMPD）。小鼠口服LD50为935.4 mg/kg,95％可信限为852.7～1021.4 mg/kg。小鼠TMPD急性中毒症状与山羊冰川棘豆自然中毒症状基本相似。
The alkaloid crystal I isolated from glacial crazyweed ( Oxytropis glacialis Benth ex Bye) in Ali prefecture in Tibet was identified as 2,2,6,6-tetramethyl-4-piperidone (TMPD) with infrared spectrophotometer, nuclear magnetic resonance spectrophotometer and data base system. Its oral LD50 was 935.4 mg/kg with 95% possibility of 852.7-1 021.4 mg/kg. The mice poisoned by TMPD showed the same symptomes as the sheep poisoned by glacial crazyweed.
出处
《畜牧与兽医》
北大核心
2002年第5期12-13,共2页
Animal Husbandry & Veterinary Medicine
基金
陕西省援藏课题(0060C8)
关键词
西藏
阿里地区
冰川棘豆
毒性
生物碱
Oxytropis glacialis
crazyweed
alkaloid
2,2,6,6-tetramethy1-4-piperisdone
toxicity
