浙江省2000年肾综合征出血热监测分析

Surveillance of Haemorrhagic Fever with Renal Syndrome(HFRS) in Zhejiang Province

为探索肾综合征出血热 (HFRS)流行特征 ,以制定有针对性的防治措施。采用间接免疫荧光法 (I FAT)检测EHF病人血清中抗体 ,采用直接免疫荧光法 (FAT)检测鼠肺汉坦病毒 (HV)抗原。结果表明 ,全省 15 0 7例病人 ,主要分布在浙东和浙西丘陵区、浙南山区 ,5、6月及 12月和翌年 1月为二个发病高峰 ,青壮年农民发病最多。今后应对以姬鼠型为主的混合型疫区选择双价疫苗进行预防接种 ,以降低发病率。

Purpose: To study the epidemiological characteristics and make the preventive strategy of HFRS. Method: FAT was used to detected HV antigen in lungs of mouse, and IFAT for antibody detection in HFRS patients. Result: All 1507 cases in whole province were mainly distributed in east west and south hill areas of Zhejiang province. May, June and December were the two peak periods of HFRS in Zhejiang. Most of the cases were young strong peasants. Conclusion: Apodemus agrarius was the main kind of mouse in mixed type areas, we should select bivalent vaccine for decreasing the incidence rate of HFRS.