摘要
利用二苯基二氯化锗和二硫代氨基甲酸盐反应,合成了8种二苯基锗二硫代氨基甲酸衍生物.通过元素分析、红外光谱、核磁共振氢谱和质谱对其结构进行了表征.初步生物活性测试结果表明,该类化合物对KB癌细胞具有一定的抑制活性.
The diphenylgermanium dithiocarbamates Ph2Ge(S2CR)2(Ⅰ-Ⅷ)have been synthesized by the reaction of Ph2GeCl2 with RCS2Na in CH2C12 solvent. Their IR,1H-NMR,UV spectra and in vitro antitumour activity are discussed. It is shown that these dithiocarbamates are mon-dentate ligands in the mentioned germanium com-plexex(Ⅰ-Ⅷ).
出处
《聊城师院学报(自然科学版)》
2001年第4期6-9,共4页
Journal of Liaocheng Teachers University(Natural Science Edition)
基金
山东省自然科学基金资助项目(Y2000B08)