摘要
为探讨儿童行为问题发生状况与外周血5-羟色胺(5-HT)浓度变化的关系,用Achenbach儿童行为量表筛查4～16岁儿童行为问题发生率,检测其外周血5-HT浓度,与正常儿童比较。结果,行为问题组5-HT浓度与正常组儿童无显著性差异(t=1.0860,P>0.05),内向性行为问题组儿童5-HT浓度显著高于正常组(t=2.4450,P<0.05),外向性行为问题组5-HT浓度低于正常组,但无显著性差异(t=0.2732,P>0.05),内向性行为问题组5-HT显著高于外向性行为问题组(t=2.1126,P<0.05)。提示,儿童行为问题的发生与外周血5-HT浓度改变有关,5-HT是儿童行为问题发生的物质基础之一。
In order to investigate the relationship between child behavior problem and the concentration of 5-HT in serum, the incidence of child behavior problem for children aged 4-16 years old were screened with Achenbach Child Behavior Checklist, the concentrations of 5-HT in serum determined and compared with normal children. Results: There was no significant difference in 5-HT concentration between behavior problem and normal groups(t=1. 0860、P>0. 05) ;5-HT concentration of introversion group was obviously higher than that of norms(t = 2. 4450、P<0. 05) ;5-HT concentration of extraversion group was lower than that of norms, but the difference was not sig-nifict(t=0. 2732、P>0. 05);5-HT concentration of introversion group was significantly higher than that of extraversion one(t= 2. 1126、P>0. 05). Conclusion,the incidence of child behavior problem relates to the change of 5-HT concentration in serum, and 5-HT is one of the substance bases for the incidence of child behavior problem.
基金
河南省卫生厅基金资助项目(编号:196)
