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二茂铁基苯甲酸四乙酰葡萄糖酯的合成及其抗贫血活性 被引量:8

Synthesis and Antianemic Activity of Tetraacetyl glucosyl esters of Ferrocenyl Benzoic Acid
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摘要 Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection. Three tetraacetyl glucosyl esters of the ferrocenyl benzoic acids(compounds Ⅱ o,Ⅱ m,Ⅱ p) have been synthesized using a phase transfer catalyst(CTAB) in dichloroethane/water at 50 ℃. Their structures have been confirmed by elemental analysis, IR, 1H NMR and MS. The compounds were found to have antianemic activity. The RBC and HB values of the tested anemic rats were increased by 72 0% and 126 4%, respectively after abdomen injection.
出处 《应用化学》 CAS CSCD 北大核心 2002年第6期603-605,共3页 Chinese Journal of Applied Chemistry
关键词 二茂铁基苯甲酸乙酰葡萄糖酯 合成 抗贫血活性 抗贫血剂 结构 ferrocenyl benzoic acid,tetraacetyl glucosyl ester,synthesis,antianemic activity
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