摘要
在自制的涂敷型纤维素 三 (3,5 二甲基苯基氨基甲酸酯 ) (CDMPC)手性固定相上拆分了一些结构相似的有机硒手性化合物 ,详细考察了三元流动相对手性拆分的影响 ,并探讨了溶质分子与手性固定相相互作用的模式。实验结果表明 :在二元流动相中加入极少量的质子性改性剂 (醇 )或非质子性改性剂 (乙腈 ) ,可使溶质的保留和手性拆分发生较大的变化。
The chiral separation of some chiral compounds with similar structure on the cellulose tris (3,5 dimethylphenylcarbamate) chiral stationary phase prepared by us was obtained. Ternary mobile phases influencing chiral recognition were investigated. A mode of interaction between the structural character of samples and chiral stationary phase is discussed. The results indicated that the retention and chiral separation of the analytes had a bigger change with minute addition of alcohols or acetonitrile as modifier in n hexane/2 propanol (80/20,volume ratio) binary mobile phase.
出处
《色谱》
CAS
CSCD
北大核心
2002年第3期241-244,共4页
Chinese Journal of Chromatography
基金
中国科学院重点基金 (批准号 :KY95 S1 2 0 5 )
