无机载体试剂作用下苯骈三氮唑的N-烷化

N-ALKYLATION BY USING THE INORGANIC SUPPORTED REAGENT FOR BENZOTRIAZOLE

报道了无机载体试剂KOH/Al_2O_3、NaOH/Al_2O_3和K_2CO_3/Al_2O_3在苯骈三氮唑的N-烷化中的应用,详细地研究了在不同的烷化剂和溶剂中,这些无机载体试剂的反应活性。

The case of studying N-allcylation by using the inorganic supported reagent for benzotriazole was reported. The inorganicsupported reagent was composed of potassium hydroxide and sodiumhydroxide and potassium carbonate separately supported on alumina. Theorder of catalyst activity for the inorganic supported reagent was KOH/Al_2O_3>K_2CO_3/Al_2O_3>NaOH/Al_2O_3, and the catalyst activity of the inor-ganic supported reagent was increased according to concentration of basicaction. Particularly, comparing with dehydrated potassium carbonate asbinding acid agent, the catalytic action of the new supported reagentK_2CO_3/Al_2O_3 was much more powerful than dehydrated polassium carbonate,and also it could chang the way of the reaction. When suitable solventwas selected, the reaction effect of this supported reagent was good.