光与生物组织相互作用模型及图像重建

Non-invasive Sensing Lesions in Tissues with Light

为了得到能用于诊断的光学图像,人们在不断研究图像的重建过程以及求解其反演问题,该问题基于这样一种假设:给出组织表面测量获得的一系列点出射光的分布,组织内部存在唯一的三维散射与吸收分布与其对应。因此,图像的重建就成为应用适当的光子传输模型求解其反演问题。为此发展了各种模式及图像重建方法。讨论了现仍存在的一些需要克服的问题。

The desire for a diagnostic optical imaging modality has motivated the development of image reconstruction proceduresinvolving solution of the inverse Problem. This approach is besed on the assumption that, given a set of measurements of transmittedlight between pairs of points on the surface of an object, there exists, a unique three-dimensional distribution of internal scatterers andabsorbers which would yield that set.Thus imaging becomes a task of solving an inverse problem using an appropriate model of photontransport. In this paper, we examine the models that have been developed for this task, and review current approaches to imagereconstruction. Finally we discuss some of the fundamental problems that must be addressed before optical tomography can beconsidered to be an understood problem and its full potential can be realized.