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维生素E琥珀酸酯抗肿瘤的信号传导机制 被引量:2

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摘要 维生素E琥珀酸酯是维生素E的衍生物 ,具有选择性抑制肿瘤细胞生长的作用 ,其抗肿瘤作用机制复杂。本文综述维生素E琥珀酸酯对细胞第一信使系统 (TGF β信号传导、Fas信号传导等 )、第二信使系统(Ca2 + 、cAMP)及其它如细胞周期信号系统等的作用 ,为探讨维生素E琥珀酸酯抗肿瘤的信号传导机制及临床应用提供基础。
出处 《国外医学(卫生学分册)》 2002年第3期136-140,共5页 Foreign Medical Sciences(Section of Hygiene)
基金 国家自然科学基金 (39870 6 77)
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  • 11,Artur Y, Cal MJ, Covi G, et al. Updating of relative data on tocopherols in clinical biochemistry. Ann Bio Clin (Paris),1994;52(1):9—31
  • 22,Prasad KN, Edwards-Prasad J. Vitamin E and cancer prevention:recent advances and future potentials. J Am Coll Nutr,1992,11:487—500
  • 33,Sporn MB, Roberts AB. Interactions of retinoid and transforming growth factor-beta in regulation of cell differentiation and proliferation. Mol Endocrinol,1991,5:3—7
  • 44,Sies H, Stahl W, Sundquist AR. Antioxidant functions of vitamins. Vitamins E and C, beta-carotene, and other carotenoids. Ann N Y Acad Sci,1992,669(30):7—20
  • 55,Rama BN, Prasad N. Study on the specificity of alpha tocopheryl(Vitamin E) acid succinate effect on melanoma. glioma and neuroblastoma cells in culture. Proc Soc Exp Biol Med,1983,174:302—307
  • 66,Isral K, Sander BG, Kline K. RRR-α-tocopheryl succinate inhibits the proliferation of human prostatic tumor cells with defective cell cycle/differentiation pathways. Nutr Cancer,1995,24:161—169
  • 77,Turley JM, Sanders BG, Kline K. RRR-α-tocopheryl succinate modulation of human promyclocytic leukemia(HL 60) cell proliferation and differentiation. Nutr Cancer,1992,18:201—213
  • 88,Charpentier A, Simmons-Menchaca M, Yu W, et al. RRR-α-tocopheryl succinate enhances TGF-β1,-β2 and-β3 and TGF-βR-Ⅱ expression by human MDA-MB-435 breast cancer cells. Nutr Cancer,1996,26:237—250
  • 99,Fariss M. The selective antiproliferative effects of α-tocopheryl hemisuccinate ang cholestery1 hemisucccinate on murine leukemia cells result from the action of the intact compounds. Cancer Res,1994,54:3346—3351

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