摘要
目的:为研究精索静脉曲张(varicocele,VC)对大鼠附睾组织重量和IL-1的影响。方法:以Wistar雄性大鼠为实验对象,采用部分结扎左肾静脉及左髂总静脉之间的交通支,造成大鼠VC模型。实验分手术结扎组(A组,n=30)和手术非结扎组(B组,n=20)。结果:A组左侧附睾重量和IL-1含量均显著高于B组左侧附睾(P<0.01),而A组右侧附睾与B组右侧附睾重量和IL-1含量比较无差异(P>0.05)。结论:VC时附睾重量、IL-1变化,可能是造成VC时附睾损伤、精子生成障碍甚至不育的原因。
Objectives: To evaluate the effect of interlukin-1 (IL-1) and weights on epididymides in rats with varicocele(vc). Methods: male adult Wistar rats were divided into 2 groups randomly:varicocele group(group A, n=30)and contrast group(group B ,n=20). Results: IL-1 Level and weights of left epididymides in group A were higher than those of group B (P<0.01); IL-1 Leves and weights of right epididymides between two groups were not significantly different (P>0.05). Conclusions: The changes in IL-1 Level and weights in the epididymides in rats with varicocele might account for epididymides damage and disturbaace of spermatogenesis and even infertility.
出处
《黑龙江医药科学》
2002年第3期9-9,共1页
Heilongjiang Medicine and Pharmacy
