孕妇缺铁性贫血561例调查及体内铁状况分析

An investigation of iron deficient anemia and analysis of the associated iron metabolic status in 561 pregnant women.

目的 调查了解孕妇体内铁代谢状况及影响贫血发生的因素 ,提出预防措施。方法 对 5 6 1例孕妇进行血红蛋白 (Hb)、血清铁 (Fe)、血铁蛋白 (SF)、运铁蛋白饱和度 (TS)、血锌卟啉 (ZPP)进行测定 ,并对有关影响因素实行专人问卷调查。结果 妊娠缺铁性贫血的发生率为 17 2 9%,随着孕周的进展贫血发生率增高 ,孕 2 0周后贫血发生率上升显著 ,SF、Fe、TS下降明显 ,孕 2 8～ 36周时贫血发生率最高达 2 9 91%,铁缺乏症发生率高达 82 0 5 %,此阶段孕妇的Fe、SF、TS降至最低 ,处于贮铁耗尽状态 ,ZPP显著上升。结论 建议对孕妇的补铁可从孕 12周后开始。孕 2 8周后Hb <10 5

Objective To investigate the iron metabolic status and the influencing factors of anemia in the pregnant women and provide preventive methods.Methods Hemoglobulin(Hb),serum iron(Fe),serum ferritin(SF),transported satuation(TS)and zinc protoporphyrin(ZPP)were measured in 561 pregnant women.Meanwhile,question protocals were specially used in the above cases.Results The incidence of IDA in the pregnancy was 17\^29% and could be higher with the development of pregnancy.After 20 weeks of pregnancy,the incidence of IDA markedly increased accompanied by the decreased Fe,SF and TS,especially during the 28～36 weeks of pregnancy,which reached the peak with the incidence of 29\^91%.82\^05% of cases showed iron deficiency in this stage,and Fe,SF and TS decreased to the lowest level and the stored iron was almosted exhausted and ZPP increased.Conclusion After 12 weeks of pregnancy,women should be suggested to be supplemented with iron.It is also suggested those pregant women with gestational age older than 28 weeks with the Hb levels of less than 105g/L should be considered as IDA and should be treated with iron supplement.