子宫肌瘤动脉栓塞疗法的临床研究

Clinical Study on the Treatment of Uterine Fibroid by Uterine Artery Embolization

目的 总结 5 5例子宫肌瘤患者动脉栓塞治疗的经验并评价其临床疗效。方法 5 5例接受子宫动脉栓塞治疗的子宫肌瘤患者 ,5 4例获随访观察 ,主要观察临床症状改变及肌瘤体积与子宫体积变化 ,并通过观察栓塞后月经改变及卵巢内分泌功能测试 ,了解卵巢功能改变。结果 总症状改善率达 10 0 % ,月经恢复正常者为 94.3% (33/35 ) ,3例出现闭经 ,所有患者术后 6个月血红蛋白均达正常水平。栓后 3个月、6个月、12个月组肌瘤平均缩小分别为 5 5 .5 % ,6 9.0 % ,82 .4% ,子宫体积平均缩小分别为 44 .5 % ,5 2 .8% ,6 4.7% ,4例患者栓后 1周～半年内经阴道排出坏死肌瘤组织。卵巢内分泌功能测试栓塞前后各年龄组变化无明显差异。结论 UAE是一种安全有效的新技术 ,对卵巢功能无明显影响。

Objective To summarize the experience and assess the effectiveness of uterine artery embolization(UAE).Methods 55 cases of uterine fibroids were treated by uterine artery embolization, 54 patients were followed up. The changes of fibroid size and uterine volume were observed. The change of ovarian function after UAE was made by observing mensis and testing ovarian hormones.Results The symptoms of all patients were improved, including the control of menorrhagia in 33/35, 3 patients had amenorrhea. All the patients' Hb count achieved normal level after 6 months. Average decrease of fibroid size after 3, 6, 12 months was 55.5%, 69.0%, and 64.7% respectively. 4 patients had discharged necrotic fibroid tissue from vaginal within 1 week to 6 months after UAE. There was no significant difference in ovarian hormone level before and after UAE.Conclusion UAE is a safety and effective procedure for treatment of uterine fibroid and has no side effect on ovarian function.