摘要
目的 :探讨限量饮酒所致血液化学成分的改变及中草药的防护功效。方法 :选用 14名健康志愿者 ,观察口服 5 6°白酒 (1ml/kg体重 )前后不同时间血液中酒精浓度及TP、Alb、Ua、Glu、CO2 、Urea、Cr、TC、TG、ApoAI、ApoB、Ca和P的变化 ;并与口服中草药解酒液进行预防的自身对照组进行比较。结果 :饮酒前后血清TP、Alb、Ua、Cr、TC、Ca及Mg基本保持恒定 ,P、TG、ApoAI和ApoB均有不同程度的升高 (P <0 0 5或P <0 0 1) ,而Glu、Urea和CO2 则呈降低趋势 (P <0 0 5或P <0 0 1)。服用中草药解酒液预防后 ,对TP、Alb、ApoB、Ua及Mg基本无影响 ,但可使血清Ca、P、Urea、Cr、TC、TG、ApoAI明显降低 ,同时使Glu和CO2 恢复正常。结论 :即使少量饮酒也会造成部分血液化学成分明显改变 ,解酒液可一定程度抑制酒精代谢、促进排泄并能纠正酒精所致血液化学成分的改变。
Objective:To investigate the effects of limited alcohol consumption induced the blood chemical parameters changes and the protective effects of herbal medicine in vivo.Methods:The changes of serum alcohol and TP?Alb?Ua?Glu?CO 2?Urea?Cr?TC?TG?ApoAI?ApoB?Caand Phave been studied before and after alcohol consuming (1ml/kg) in 14 volunteers. Meanwhile a self-controlled herbal medicine protection group has been comparatively observed. Results:The serum TP?Alb?Ua?Cr?TC?Caand Mghave not been found obvious changes, but serum P?TG?ApoAIand ApoBincreased(P<0.05 or P<0.01),whereas serum Glu?Ureaand CO 2decreased after alcohol consumption(P<0.05 or P<0.01). The serum TP?Alb?ApoB?Uaand Mghave no obvious changes in herbal medicine group. But the serum Ca?P?Urea?Cr?TC?TG?ApoAIdecreased markedly after using herbal medicine, meanwhile the decreased serum Gluand CO 2have been recovered.Conclusions:Even the limited alcohol consumption could be caused the marked changes of some blood chemical parameters and the herbal medicine could inhibit the side effects of alcohol to the body.
出处
《军医进修学院学报》
CAS
2002年第2期86-88,共3页
Academic Journal of Pla Postgraduate Medical School
基金
"十五"军队科研基金项目 ( 0 1MB0 72 )
