保留NAC的改良乳癌根治术肿瘤学危险性研究

Study of oncologic risk of modified radical mastectomy with NAC preservation

目的 :探讨保留乳头乳晕复合体 (nipple areolarcomplex ,NAC)的改良乳癌根治术的肿瘤学危险性。方法 :对 40例乳腺癌标本的NAC采用横断多层面取材方法进行病理检查 ,运用统计学方法分析肿瘤大小、分期、位置、NAC及皮肤临床表现等与NAC受累的关系。结果 :全部 40例中 ,NAC受累 7例 ,占 17 5 %。肿瘤大小、分期、NAC及皮肤临床表现与NAC受累明显相关 (P <0 0 0 2 )。结论 :对早期乳腺癌 ,只要无NAC及皮肤异常临床表现 ,可考虑行保留NAC的改良乳腺癌根治术。

Objective:to discuss the oncologic risk of modified radical mastectomy with NAC preservation. Methods: Multiple cross sections of NAC from 40 breast cancer specimens were examined to find out the rate of NAC involvement. The relation between tumor size, stage, NAC clinical manifestation and the involvement of the NAC was analysed statistically.Results: 7 of the 40 cases were found out NAC involvement(17.5%).The relation between tumor size, stage, NAC clinical manifestation and the involvement of the NAC was statistic significance (P<0.002). Conclusion:Modified radical mastectomy with NAC preservation should be accepted if early stage breast cancer without abnormal skin clinical manifestation.