食管中下段组织病理学对照研究

COMPARISON STUDY OF HISTOPATHOLOGY OF MIDDLE AND LOWER SEGMENT OF ESOPHAGUS

本文报告食管癌高发区(河南辉县)125例(男76例,女49例)食管中、下段粘膜组织病理学检查结果。男性食管中段正常,乳头升高,基底细胞过度增生和间变的检出率分别为:31.58％,31.58％,61.84％和1.32％;女性分别为:32.65％,36.73％,48.98％,4.08％。同一组病人食管下段正常、乳头升高、基底细胞过度增生和间变的检出率男性分别为:51.53％、27.63％、38.16％和5.26％;女性分别为57.14％,22.45％,34.69％和0.00％。结果提示,食管中、下段组织学改变不同,中段乳头升高,基底细胞过程增生的检出率明显高于下段,而间变的检出率男性下段高于中段,女性下段低于中段(P<0.05,t检验)。

The histopathological result of middle and lower esophageal mucosal biopsy of 125 subjects (M76, F 49) in Huixian, Henan Province (a high-risk area for csophagcal cancer ) are reported. In the middle segment of csophagus, the incidence of normal, papillac upgrowth, basal cch hyperpasia and dysplasis was 31. 58, 31. 58, 61. 84, and 1. 32% respectively in male, and 32. 65, 36. 73, 48. 98 and 4. 08% respectively in female. In lower segment of the esophagus, the incidence was 51. 31, 27. 63, 38. 16 and 5. 26% rcspectively in male, and 57. 14, 22. 45, 34. 69 and 0. 00% respectively in famale. The results indicated that histopathological changes were diffrent in middle and lower segment of the esophagus. The incidence of papillae upgrowth, basal cell hypcrplasia was higher in middle than that in lower both in male and famale, however, dysplasia in middle was more common that in lower only in female.