肾综合征出血热特异性抗体调查研究

Survey on Specificity Antibody Against Hemorrhagic Fever with Renal Syndrome

目的 :了解肾综合征出血热 (HFRS)病人血清特异性抗体特征。方法 :采用间接免疫荧光法 (IFAT) ,检测HFRS现症病人及患病后 1～ 5年血清抗体滴度。结果 :调查现症病人 5 5例 ,其血清抗体IgG阳性率 90 .91% ;调查患病后 1～ 5年血清抗体 61份 ,阳性率为 88.5 2 %。结论 :本病病后能产生相应的特异性抗体 ,血清抗体滴度保持较高水平 ,有持久的病后免疫 。

Objective: To investigate the feature of blood specificity antibody against hemorrhagic fever with renal syndrome (HFRS) virus in the patients. Methods:The blood antibody titer against HFRS were tested with IFAT in the patients including who recovered 1-5 years ago. Results: The antibody (IgG) positive rate of 55 patients was 90.91 %, of 61 patients who recovered from HFRS 1-5 years ago was 88.52 %. Conclusion:The pationts can produce corresponding specificity antibody and have lasting immunity. The titer of blood antibody keeps higher level,but it reduces gradually.