7-hydroxystaurosporine:一种有广泛前景的抗肿瘤药物(英文)
7-hydroxystaurosporine: A profound anti-cancer agent
摘要
7_hydroxystaurosporine是一种激活enzymeC类型选择性抑制剂。大量体内外实验已经证实UCN_01是一种有效的新抗肿瘤药物 ,包括抑制肿瘤的生长 ,阻断肿瘤细胞生长周期 ,导致肿瘤细胞凋亡 ,抑制肿瘤浸润和转移等。在美国和日本UCN_01已经进入临床试验阶段。这篇综述总结了有关UCN_01抗肿瘤研究的文献 。
出处
《中国临床药理学与治疗学》
CAS
CSCD
2001年第1期81-87,共7页
Chinese Journal of Clinical Pharmacology and Therapeutics
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