骨髓增生异常综合征30例分析

ANALYSIS OF 30 CASES WITH MYELODYSPLASTIC SYNDROME

本文报告了30例骨髓增生异常综合征(Myelodysplastic Syndrome, MDS)。本病起病隐袭,病往长,周围血中至岁一系列细胞数减少及形态学异常。骨髓多数增生活跃,至少有两系以上表现为病态造血。讨论了MDS亚型分类的建议,是否存在铁利用障碍。并不在于环形铁粒幼细胞的多少。难治性贫血(RA)和不典型再障的鉴别在于动态观察外周血、骨髓有无病态造血。

Thirty cases of Myclodysplastic Syndr me was reported in this article.The cases in the series revealed that tthe onset of the disease was insidious and the courses were rather long.The numbers of cell at least in on series was decreased in periphenal blood, of which the morphology of cells was abnormal. The myeloproliferation was active in the majority of cases. Pathogenic hemopoiesis may be observed in the two series of cells or more.The proposal of subtype classification was discussed. It is probably that the iron utilization would be obstructive, other than the numbers of ringed sideroblasts.The differential diagnosis of refractory anemia and alypical aplastic anemia may depend upon developing observation, whether it would be present pathogenic hemopoiesis in peripheral blood and bone marrow.