摘要
凝血因子Ⅶ是外源性凝血途径启动的靶因子,其在正常人血浆中浓度为0.5～2.0 mg/L.前瞻性研究表明,血浆游离因子Ⅶ(Ⅶa)及Ⅶ活性(Ⅶ:C)是血栓形成的独立危险因素.FⅦ的基因多态性与心血管事件发生有关,并可导致FⅦa均值增高5倍.本文仅就FⅦ基因的多态性对FⅦ水平影响及其临床意义做一综述.
出处
《血栓与止血学》
2002年第2期87-89,共3页
Chinese Journal of Thrombosis and Hemostasis
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