摘要
目的观察急性心肌梗死 (AMI)溶栓后血管再通和未通者与未溶栓者血清肌钙蛋白的动态变化。方法定量测定 93例 AMI患者的心肌肌钙蛋白 I(c Tn I) ,以 >10 0 ng/ L作为阳性判定值。结果溶栓再通者 c Tn I峰值较未通组与未溶栓组显著增高 (P<0 .0 5 ) ,且峰值增大 ,峰值时间提前 8小时 ,再通组 c Tn I恢复正常时间平均为 (13 0± 3 8)小时 ,较未通者提前 60小时。结论溶栓后动态测定血清c Tn I浓度、峰值时间 ,可作为判断溶栓成功的指标之一。
Objective To observe the dynamic changes of troponin I (cTn I) in acute myocardial infarction patients with thrombolytic and non thrombolytic therapy.Methods cTn I was measured in 93 AMI patients.The positive criteria of judgement were over 100ng/L.Results The peak value of cTn I was much higher in thrombolytic recanalyzed group than in thrombolytic non recanalized group and non thrombolytic group (P<0.05).When the peak value increased,the value got to peak ahead of 8 hours.The average time needed for cTnI to come to normal was (130±38) hours in recanalized group,which was ahead of 60 hours as compared to non recanalized group.Conclusion The dynamic monitoring value of cTn I in serum and peak value time is one of the markers of thrombolytic recanalization of assessment.
出处
《中国综合临床》
北大核心
2002年第6期508-509,共2页
Clinical Medicine of China
