幽门螺杆菌感染根除与老年消化性溃疡发生、复发关系的研究

Study on the relationship between helicobacter pylori infection eradication and old people peptic ulcer recurrence

目的 探讨老年消化性溃疡发生、复发与幽门螺杆菌 (Hp)感染的关系。方法 应用 PCR法对 78例老年性消化性溃疡幽门螺杆菌感染及幽门螺杆菌感染根除治疗后半年、 1年幽门螺杆菌再感染者进行了测定。结果 幽门螺杆菌检出率老年组明显高于青年组 ,Hp根治率青年组明显高于老年组 ,经 Hp根除治疗组溃疡愈合率明显高于未根除治疗组。结论 老年消化性溃疡发生与幽门螺杆菌感染密切相关 ,在溃疡治疗中 ,根除

Objective To probe into the relationship between helicobacter pylori (Hp) reinfection and old people peptic ulcer recurrence. Methods Hp in gastric antral mucosal tissue of 78 old people peptic ulcer patients was detected by polymerase chain reaction (PCR) and urease methods after one year of Hp eradication, Hp reinfection and ulcer recurrence were also observed. Results The rate of Hp infection in old patient group was higher than that in young group and the rate of Hp eradication in young group was higher than that in old ones. Conclusions There was close relationship between helicobacter pylori and old people peptic ulcer. It was important in reducing ulcer recurrence that Hp was eradicated from ulcer patients.