羧甲基淀粉溶液治疗儿童内源性哮喘43例

Carboxymethyl starch solution in the treatment of intrinsic asthma in 43 children

选择内源性哮喘患儿62例,按双盲法分成治疗组43例,和对照组19例。治疗组口服CMS溶液后的总有效率为72％,明显高于对照组;且服药后血PHA及唾液SIgA值均明显升高;而血嗜酸粒细胞值显著下降。剂量以45％CMS溶液0.75mL/(kg·d)分2次口服,6mo为一个疗程。除个别患儿初服时有一过性腹泻外,末见其它毒副作用。

Sixty-two children with intrinsic asthma are reported. Fourty-three children received 45% carboxymethyl starch 0.75mL/(kg-d) far a course of 3-6mo, Nineteen children were controlled. The total efficacy rate was 72% (P<0.01). The serum PHA and SIgA showed marked increases (P<0.01 and P<0.05, respectively). The blood eosinophil count showed a marked decrease (P<0.01). It yielded no adverse effects. Results suggest that there is an augmentation in cellular immunologic function.