特布他林气雾剂治疗支气管哮喘

Treatment of bronchial asthma with terbutaline aerosol

本文选择100例稳定型慢性支气管哮喘患者,随机分成2组。分别喷用特布他林气雾剂2喷即0.5mg或安慰剂气雾剂。经用药前后肺功能指标(FEV_1)和临床症状比较,结果表明特布他林气雾剂明显优于安慰剂气雾剂(P<0.005)。起效快,平喘作用维持时间达2h左右,副作用少,比较安全。

One hundred patients with chronic stable bronchial asthma (basic PEFR > 150L/min) were randomly divided into two groups, treated with terbutaline aerosol (2 puffs= 0.5mg) and placebo nebula respectively. Pulmonary functions(FEV1),clinical symptoms and physical signs before and after the treatment were compared and revealed terbutaline aerosol was significantly superior than placebo nebula (P< 0.005). Terbutaline aerosol proved much safer, with very slight side effects, and provided a fast onset and an approximately 2 h duration of effect. No obvious change in the heart rate and blood pressure were seen.