他汀类药物抗动脉粥样硬化的可能机制
被引量:2
The possible mechanism of statins' interfering in atherosclerosis
摘要
本文概述了动脉粥样硬化斑块的形成、发展和破裂的机制 。
The essay summarizes the mechanism of atherosclerosis and the possible mechanism of statins' interfering in it.
出处
《中国心血管杂志》
2002年第3期215-217,共3页
Chinese Journal of Cardiovascular Medicine
参考文献10
-
1Abedi H,Zachary j. Signalling mechanisms in the regulation of vascular cell migration. Cardiovasc Res. 1995 ; 30 : 544- 556.
-
2Yonemitsu Y,Kaneda Y ,Tanaka S.et al. Transfer of wildtype p53 gene effectively inhibits vascular smooth muscle cell proliferation in vitro and vivo. Cire Res, 1998 ; 82 : 147-155.
-
3Bellosta S, Bernini F, Ferri N. et al. Direct vascular effects of HMG- COA zeductase inhibitozs. Atherosclernsis, 1998, 137(Suppl) . S101-S109.
-
4Sindemann J,Weigel K. Muller JG.et al. Induction of p53 and interleukin-8 by HMG-COA reductase inhibitors in human corauary smooth muscle cells (Abstract). Eur Heart J, 1997,18 (Suppl);371.
-
5Clair rw. Pathogenesis of atberosclerosis. Cardiology in Review. 1997.5:14-24.
-
6Werle M ,Durst D,Knopt D ,et al. Activation of mitogen activated protein kinase by MCP-1 in human endothelial cells is suppressed by cerivaststin. Basic Res Cardial, 1999.20 : 58-69.
-
7Ikeda U,Shimada K. Statins and monocytes. Lancet, 1999,353:2070.
-
8Masaaki K,Kurose I, Russell J, et al. Effect of fiuvastatin on leukocyte-endothelial cell adhesion in kypercholeszerolemic rats. Artertosclet Tkromb Vase Biol,1997,17:1521-1555.
-
9Serruys PW Foley DP, Jackson G,et al. A randomized placebocontroled trial of fluvaszatin for prevention of restenosis after successful coronary ballon angioplasty:final results of the Fluvastatin Angigplasty Restenosis(FLARE) Trial. Eur Heart J,1999,90:58-69.
-
10Moron DJ,Fazio S, Linton MF. Current perspectives an statins.Circulation ,9000,101:207-213.
同被引文献16
-
1Davies MJ.The Pathophysiology of acute coronary syndromes.Heart,2000,83(3):361~366.
-
2Hocke. Angiotropin treatment prevents flap necrosis and enhances dermal regeneration in rabbits [ J ]. Arch Surg, 1989; 124 ( 6 ): 693-698.
-
3Marks GS, Brien JF, Nakatsu K, et al. Dose carbon monoxide have a physiological function? [ J ]. Trends Pharmacol Sci, 1991, 12: 185-188.
-
4Isner J M. Myocardial gene therapy[J].Nature,2002,415(6868):234-239.
-
5Mousa A. Mechanisms of angiogenesis in vascular disorders: Potential therapeutic targets[J]. Drugs Fut, 1998,23( 1 ) :51-60.
-
6Sugiyarna T, Lee JD, Shimizu H, et al. Influence of treated blood pressure on progression of slient cerebral infarction[ J] .J Hypertents,1999,17(5) :679-684.
-
7Chien S, US, Shyy YJ. Effects of mechanical forces on signal transduction and gene expression in endothelial cells [ J ].Hypertension, 1998,31(1-2): 162-169.
-
8张建军,陈书艳,张爱兵,马大列,陈思聪,张国元,吴宗贵.酸性成纤维细胞生长因子对微血管生成的影响[J].中华心血管病杂志,1998,26(2):97-97. 被引量:5
-
9汤健.生物活性蛋白的功能多样性与分子内调控[J].中华医学杂志,2000,80(10):727-728. 被引量:12
-
10吴以岭.从络病学说论治冠心病心绞痛[J].中国中医基础医学杂志,2001,7(4):71-74. 被引量:113
二级引证文献51
-
1李敏,王清海(指导).王清海从血脉理论论治动脉粥样硬化经验[J].湖南中医杂志,2020,0(2):18-20. 被引量:2
-
2吴海深,张玉岭,牛云霞.中西医结合治疗老年冠状动脉粥样硬化性心脏病心绞痛66例疗效观察[J].河北中医,2007,29(7):613-614. 被引量:3
-
3高宇,张军平.“阳微阴弦”在冠心病介入术后新解初探[J].辽宁中医杂志,2010,37(S1):53-54. 被引量:1
-
4吴茂林.从毒损络瘀论治糖尿病阳痿思路探析[J].中医研究,2007,20(5):9-10. 被引量:15
-
5张小红.活血化瘀法治疗短暂脑缺血发作38例[J].光明中医,2007,22(10). 被引量:3
-
6张哲,杨关林,张会永,陈民,陈岩,罗智博.以外科瘤痈论治动脉粥样硬化斑块设想探要[J].辽宁中医杂志,2008,35(2):201-202. 被引量:6
-
7陈圆,杨博华.中药促进血管新生研究进展[J].中国中西医结合外科杂志,2008,14(6):597-599. 被引量:14
-
8彭立,张军平.易损斑块与阴虚毒瘀病机相关理论的探讨[J].中华中医药学刊,2009,27(5):970-971. 被引量:20
-
9彭立,张军平.四妙勇安汤防治动脉粥样硬化性疾病的临床应用及作用机制研究[J].天津中医药,2009,26(4):351-352. 被引量:9
-
10张军平,许颖智,李明,李良军,彭立,张光银,杨萃,周亚男.补肾抗衰片对实验性动脉粥样硬化家兔的NF-κB及炎症因子的影响[J].中国中西医结合杂志,2009,29(9):816-820. 被引量:31
-
1张玉英,范维琥.阿司匹林抵抗[J].国外医学(心血管疾病分册),2004,31(5):270-272. 被引量:5
-
2段淑娟.不同剂量阿托伐他汀钙片治疗急性脑梗死的临床疗效观察[J].中国实用医药,2016,11(16):164-165. 被引量:2
-
3刘卫民,孙秀兰.大剂量辛伐他汀治疗急性心肌梗死75例临床分析[J].中国煤炭工业医学杂志,2009,12(1):74-75.
-
4卜秀玲,梁敏,张文,王建筑,李军.阿司匹林抵抗[J].食品与药品,2007,9(1):72-75.
-
5喻东山.精神药物与体重增加[J].医药导报,2000,19(4):315-316. 被引量:1
-
6刘时武,丁世芳.他汀类药物的非调脂作用[J].华南国防医学杂志,2008,22(2):63-65. 被引量:13
-
7王华,沈玉先,等.褪黑素对免疫性肝损伤的保护作用及其可能机制[J].中国药理通讯,2002,19(4):53-53.
-
8刘建平.用好他汀类保护心血管[J].家庭用药,2012(10):16-17.
-
9王勇.阿托伐他汀治疗不稳定型心绞痛的临床观察[J].中国当代医药,2009,16(19):37-38. 被引量:2
-
10林素娜,厉有名.长期应用质子泵抑制剂可能增加痴呆发生风险的研究现状[J].中国临床药理学杂志,2017,33(9):849-852. 被引量:5