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天然CD4^+ CD25^+ Treg细胞的研究进展 被引量：1

Natural CD4^+ CD25^+ regulatory T cells
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摘要 天然CD4 + CD2 5 + Treg细胞在针对自身抗原和外来抗原的免疫应答中起关键控制作用 ,其缺乏或功能性的缺陷将导致多重病理性的失调。本文就近年在其产生、作用机制以及与免疫耐受的诱导关系等方面的研究进展进行了综述。 Natural CD4 +CD25 + regulatory T cells have a major role in controlling the immune response to self and foreign antigens and their absence or functional deficiency leads to multiple pathological disorders. So we focus on recent advances in the area of their generation, suppression mechanism and tolerance induction.
作者 许桂莲
机构地区 第三军医大学全军免疫学研究所
出处 《免疫学杂志》 CAS CSCD 北大核心 2002年第B06期70-74,共5页 Immunological Journal
关键词 天然CD4^+CD25^+Treg细胞 研究进展 自身免疫 CD4 +CD25 + regulatory T cells autoimmune
分类号 R392.11 [医药卫生—免疫学]
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参考文献10

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同被引文献24

  • 1李华,陆丽,刘金保,董伟华,沈守星.金黄色葡萄球菌肠毒素B对豚鼠哮喘模型Th1/Th2细胞因子的影响[J].免疫学杂志,2006,22(z1):139-141. 被引量：5
  • 2于睿莉,朱冬冬,董震.金黄色葡萄球菌肠毒素B对人鼻黏膜上皮细胞的促炎作用[J].中华耳鼻咽喉头颈外科杂志,2007,42(3):202-206. 被引量：5
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  • 7Campbell DE, Kemp AS. Proliferation and production of in- terferon-gamma (IFN- "y ) and IL-4 in response to staphylo- coccus aureus and staphylococcal superantigen in childhood atopic dermatitis [J]. Clin Exp Immunol, 1997, 107 (2): 392-397.
  • 8Hauk PJ, Wenzel SE, Trumble AE, et al. Increased T-cell receptor V T cells in bronchoalveolar lavage fluid of subjects with poorly controlled asthma: a potential role for microbial superantigens [J]. J Allergy Clin Immunol, 1999, 104(1):37-45.
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免疫学杂志
2002年 第B06期

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