自身免疫性疾病的细胞因子调节疗法

Cytokines regulating therapy of autoimmune diseases

自身免疫性疾病是一类由细胞因子、自身抗体及其联合介导的免疫性疾病。细胞因子具有双重效应 ,既可抵御和治疗某些疾病 ,也可导致和促进某些疾病的发生。因此 ,CK调节疗法有补充 添加疗法和阻断 拮抗疗法两类。细胞因子调节疗法包括给予抑制性细胞因子、IL 4、IL 10、IL 13和TGF β等 ;投给可溶性细胞因子受体 ,受体的阻断剂如IL 1受体拮抗物(IL 1ra)、抗细胞因子抗体等。CK调节疗法能阻断或干扰AID的发展。细胞因子调节疗法是自身免疫性疾病的一种可靠的治疗方法。

Autoimmune diseases are kinds of diseases that are induced by cytokines, autologous antibodies and/or their association. And cytokines have important effects in development of autoimmune diseases. Cytokines have both effects. Cytokines might control some autoimmune diseases, others might also induce or promote some autoimmune diseases. And the mechanism of cytokines regulating therapy of autoimmune diseases are to supply inhibiting cytokine,soluble cytokine receptors,antagonist of cytokines receptors ,antibody of cytokines and their association,and so on. This therapy can interrupt the development of autoimmune diseases. So cytokine regulating therapy is a reliable therapy of autoimmune diseases.