摘要
目的 :探讨抗凝药物及氮芥对肾病综合征患者尿量及纤维蛋白原的影响。方法 :记录治疗前后患者的尿量及纤维蛋白原的改变 ,对治疗前后有显著差异者进行比较。结果 :尿激酶合氮芥 ,低分子肝素及肝素治疗前后尿量改变明显 (P <0 .0 5 ) ,尿激酶、肝素及低分子肝素可明显降低血浆纤维蛋白原含量 (P <0 .0 5 )。结论 :氮芥合尿激酶 ,肝素与低分子肝素对肾病综合征患者在利尿及降纤治疗上有优势。
Objective:To evaluate the influence of anticoagulant therapy and Nitrogen mustard.on urine volume and fibrinogen in patients with nephrotic syndrome.Methods:Changes of urine volume and fibrinogen after the treatment were recorded, and these changes were compared. Results:After the treatment with urokinase plus nitrogen mustard and heparin,the volume of urime obviously increased(P<0.05).These drugs can remarkably lower the conteut of plaswa fibrinogen(P<0.01). Conclusions:The therapeutic methods of combined usage of urokinase with nitrogen mustard,Heparin and Low molecular heparin are superior in promoting diuresis and in lowering the fibrinogen in nephrotic syndrome patients.
出处
《中国中西医结合肾病杂志》
2002年第6期334-335,338,共3页
Chinese Journal of Integrated Traditional and Western Nephrology