全氟代表面活性剂水溶液囊泡性质的研究

Study on the properties of vesicles in aqueous solution of perfluorinated surfactant

通过一种新型的全氟代表面活性剂 (APFO)、水和氯化铵对形成囊泡影响的研究 ,表明APFO /H2 O /NH4Cl体系可在一定时间和较大温度范围内以及各组分含量变化较宽的范围内都能形成囊泡 .而且当温度为 4 0℃ ,NH4Cl的质量分数为 0 0 4～ 0 1 ,APFO的质量分数为 0 0 2～ 0 4 2时 ,形成的囊泡尺寸无变化 ,且能稳定存在 2 4h以上 ,为药物的包藏及缓释提供了必要条件 .

The properties of vesicles formed by perfluorinated surfactant in aqueous solution have been systematically investigated.Results showed that the vesicles are stable in a rather large temperature variation and in long time,the stability of vesicles depends on the concentration of the salt and the surfactant in solution.