心、脑血管病患者血清铁蛋白和β_2-微球蛋白的含量变化及其意义

The Changes of Serum Ferritin and β_2-microglobulin in the Cardiovascular and Cerebrovascular Diseases and Their Clinical Significance

为探讨人血清铁蛋白 (SF)和 β2 -微球蛋白 (β2 -MG)在心、脑血管疾病中的含量变化及其在临床上的应用 ,用放射免疫分析法 (RIA)分别对 2 2例冠心病、4 6例高血压、2 1例脑梗死共 89例心、脑血管疾病患者的血清进行检测 ,并与 12 1名健康人作对照。结果表明 ,冠心病、高血压及脑梗死患者血清中SF、β2 -MG的含量 ,均高于对照组 ,差异有显著性 (P <0 .0 1)。本文提示SF、β2 -MG均参与了冠心病、高血压 ,脑梗死疾病的发病机理过程 ,可作为心。

To study the changes of serum ferritin(SF) and β 2-microglobulin(β 2-MG)in the cardiovascular and cerebrovascular diseases and their clinical significance, serum SF and β 2-MG in 22 patients with coronary cardiopathy, 46 patients with hypertension and 21 patients with cerebral infarction were tested by RIA and compared with control group. The results showed that serum SF and β 2-MG in patients with the above-mentioned diseases were significantly higher than those in control group(P<0.01). Conclusion: both SF and β 2-MG participate in the pathophysiological processes, so that they may be used as references to therapeutic effectiveness and prognosis.