摘要
为探讨血透患者血清心钠素 (ANF)和甲状旁腺素 (iPTH)水平与血液透析低血压的关系 ,采用放射免疫分析和免疫放射分析法分别测定 36例维持性血透患者透析前后血清ANF和iPTH水平变化 ,并分析其与低血压的关系。结果发现 :血透患者ANF和iPTH总体水平显著高于对照组 ,透析后总体水平显著低于透析前 (P均小于 0 .0 1) ;低血压组患者透析前血清ANF和iPTH水平均高于正常血压组 (P均小于 0 .0 5 ) ;透析后低血压组患者ANF水平较透析前显著降低 (P <0 .0 5 ) ,但iPTH水平较透析前进一步增高 (P <0 .0 5 )。结论
To study the effect of ANF and iPTH on hypotension during hemodialysis, the serum ANF and iPTH levels of 36 maintenance hemodialysis patients were detected by radioimmunoassay and immunoradiometricassay. Results showed that both ANF and iPTH average levels in hemodialysis patients were markedly higher than those in normal controls( P <0.01),and decreased significatly after hemodialysis( P <0.01). Before hemodialysis, both ANF and iPTH levels in hypotensive patients were signficanntly higher than those in normotensive patients( P <0.05). After hemodialysis in hypotensive patients, ANF levels decreased significantly( P <0.05), and iPTH levels increased significantly( P <0.05). Conclusions: The high serum level of ANF and iPTH might be related to hypotension during hemodialysis.
出处
《标记免疫分析与临床》
CAS
2002年第2期73-75,共3页
Labeled Immunoassays and Clinical Medicine
基金
中山医科大学附属第三医院科研基金项目(No .974 0 )
