高校新生HBV感染的血清学分析

AN ANALYSIS OF HBV INFECTION IN FRESHMEN OF UNIVERSITIES.

目的 :了解高校新生 HBV感染状况。方法 :对 1999年入学新生用酶联免疫法 (EL ISA)检测病毒性乙型肝炎五项血清学标志 ,及测定 AL T(丙氨酸氨基转移酶 )。结果 :HBs Ag携带率为 6 .16 % ,性别间差异无显著性 (P>0 .0 5 ) ,其感染模式有 7种 ,以 HBs Ag+HBe Ag+抗 - HBc阳性 ;HBs Ag+抗 - HBe+抗 - HBc阳性 ;HBs Ag+抗 - HBc三种模式多见 ,其构成比分别为 31.38%、 2 9.79%、 2 6 .0 6 %。HBs Ag阳性者与阴性者 AL T异常率分别为 9.5 7%及 0 .70 % ,两者之间差异有显著性 (χ2 =113.0 7,P<0 .0 1)。结论 :为预防和控制乙肝在高校的传染 ,在新生中应加强乙型肝炎感染的控制和预防工作。

Objective:To investigate the situation of HBV infection in freshmen of universities.Methods:Serum five indicators of the infection of hepatitis B were detected with Enzyme-linked immune assay(ELISA),and ALT was detected in freshmen of Sichuan university in 1999.Results:The positive rate of HBsAg was 6.16%,whithout significant sex difference(P>0.05).HBV infection had seven patterns.The main HBV infection patterns were as follows;HBsAg,HBeAg and anti-HBc positive(31.38%).HBsAg,anti-HBe and anti-HBc positive(29.79%).HBsAg,anti-HBc positive(26.06%).The abnormal rate of ALT was 9 57% among the cases of positive HBsAg.abnormal ALT was 0 70% among the cases of negative HBsAg.There is an obvious difference between them on the abnormal rate of ALT(χ~2=113.07,P<0.01).Conclusion:In order to prevent the infection of hepatitis B in universities,we should to strengthen control and preventive measures in freshmen.